Peptide Information

General Information of This Peptide
Peptide ID
BTDP000202
Peptide Name
GPTX1 (Tyr32Ala)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKYVF
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Mutant Sequence
DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKAVF
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Sequence Length
34
Mass(Da)
3989
Sequence Removed Signal Peptide
DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKAVF
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Disulfide Bond
2-17;9-23;16-30
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
800 nM
 . . [1]
 Target Info    Nav1.4 IC50
>5 μM
 . . [2]
 Target Info    Nav1.5 IC50
>5 μM
 . . [3]
References
Ref 1 Blood culture series benefit may be limited to selected clinical conditions: time to reassess. Clin Microbiol Infect. 2015 Apr;21(4):332-6. doi: 10.1016/j.cmi.2014.11.019. Epub 2014 Nov 27.
Ref 2 Factors associated with Staphylococcus aureus nasal carriage among healthy people in Northern China. Clin Microbiol Infect. 2015 Feb;21(2):157-62. doi: 10.1016/j.cmi.2014.08.023. Epub 2014 Oct 29.
Ref 3 Impact of a hospital-wide multifaceted programme for reducing carbapenem-resistant Enterobacteriaceae infections in a large teaching hospital in northern Italy. Clin Microbiol Infect. 2015 Mar;21(3):242-7. doi: 10.1016/j.cmi.2014.10.020. Epub 2014 Nov 11.
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