Peptide Information

General Information of This Peptide
Peptide ID
BTDP000198
Peptide Name
GPTX1 (Trp29Ala)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKYVF
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Mutant Sequence
DCLGFMRKCIPDNDKCCRPNLVCSRTHKACKYVF
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Sequence Length
34
Mass(Da)
3966
Sequence Removed Signal Peptide
DCLGFMRKCIPDNDKCCRPNLVCSRTHKACKYVF
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Disulfide Bond
2-17;9-23;16-30
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.4 IC50
>4.5 μM
 . . [1]
 Target Info    Nav1.5 IC50
>5 μM
 . . [2]
 Target Info    Nav1.7 IC50
>5 μM
 . . [3]
References
Ref 1 Dynamics of hepatitis B virus quasispecies heterogeneity in association with nucleos(t)ide analogue treatment determined by MALDI-TOF MS. Clin Microbiol Infect. 2015 Mar;21(3):288.e1-4. doi: 10.1016/j.cmi.2014.10.004. Epub 2014 Oct 29.
Ref 2 Predicting the risk of Clostridium difficile infection following an outpatient visit: development and external validation of a pragmatic, prognostic risk score. Clin Microbiol Infect. 2015 Mar;21(3):256-62. doi: 10.1016/j.cmi.2014.11.001. Epub 2014 Nov 11.
Ref 3 In situ cobalt-cobalt oxide/N-doped carbon hybrids as superior bifunctional electrocatalysts for hydrogen and oxygen evolution. J Am Chem Soc. 2015 Feb 25;137(7):2688-94. doi: 10.1021/ja5127165. Epub 2015 Feb 17.
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