Peptide Information

General Information of This Peptide
Peptide ID
BTDP000147
Peptide Name
GPTX1 (Leu21Ala)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKYVF
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Mutant Sequence
DCLGFMRKCIPDNDKCCRPNAVCSRTHKWCKYVF
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Sequence Length
34
Mass(Da)
4053
Sequence Removed Signal Peptide
DCLGFMRKCIPDNDKCCRPNAVCSRTHKWCKYVF
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Disulfide Bond
2-17;9-23;16-30
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
190 nM
 . . [1]
 Target Info    Nav1.5 IC50
>20 μM
 . . [2]
 Target Info    Nav1.4 IC50
3.0 ± 0.7 μM
 . . [3]
References
Ref 1 High-performance liquid chromatography method for ferric iron chelators using a post-column reaction with Calcein Blue. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Mar 15;985:48-53. doi: 10.1016/j.jchromb.2015.01.027. Epub 2015 Jan 24.
Ref 2 Ensuring backwards compatibility: traditional genotyping efforts in the era of whole genome sequencing. Clin Microbiol Infect. 2015 Apr;21(4):347.e1-4. doi: 10.1016/j.cmi.2014.11.005. Epub 2014 Nov 25.
Ref 3 Whole genome characterization of hepatitis B virus quasispecies with massively parallel pyrosequencing. Clin Microbiol Infect. 2015 Mar;21(3):280-7. doi: 10.1016/j.cmi.2014.10.007. Epub 2014 Oct 29.
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