Peptide Information

General Information of This Peptide

Peptide ID	BTDP000113
Peptide Name	GPTX1 (Asn20Ala)
3D Structure	Download 2D Sequence Download FASTA 3D Structure Download PDB Source Predict by Alphafold2 ? Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence	DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKYVF Click to Show/Hide
Mutant Sequence	DCLGFMRKCIPDNDKCCRPALVCSRTHKWCKYVF Click to Show/Hide
Sequence Length	34
Mass(Da)	4038
Sequence Removed Signal Peptide	DCLGFMRKCIPDNDKCCRPALVCSRTHKWCKYVF Click to Show/Hide
Disulfide Bond	2-17;9-23;16-30
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N.A.

Full List of Activity Data of This Peptide Toxin

Target Name	Activity Data Type	Activity Data	Concentration	Note	Reference
Target Info Nav1.7	IC50	690 nM	.	.	[1]
Target Info Nav1.4	IC50	>5 μM	.	.	[2]
Target Info Nav1.5	IC50	>5 μM	.	.	[3]

References

Ref 1	Application of ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry to identify curcumin metabolites produced by human intestinal bacteria. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Mar 15;985:38-47. doi: 10.1016/j.jchromb.2015.01.014. Epub 2015 Jan 24.
Ref 2	A multicenter study of the clonal structure and resistance mechanism of KPC-producing Escherichia coli isolates in Israel. Clin Microbiol Infect. 2015 Mar;21(3):230-5. doi: 10.1016/j.cmi.2014.10.008. Epub 2014 Oct 29.
Ref 3	Ensuring backwards compatibility: traditional genotyping efforts in the era of whole genome sequencing. Clin Microbiol Infect. 2015 Apr;21(4):347.e1-4. doi: 10.1016/j.cmi.2014.11.005. Epub 2014 Nov 25.

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