Peptide Information

General Information of This Peptide
Peptide ID
BTDP000109
Peptide Name
GPTX1 (Asn13Ala)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKYVF
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Mutant Sequence
DCLGFMRKCIPDADKCCRPNLVCSRTHKWCKYVF
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Sequence Length
34
Mass(Da)
4038
Sequence Removed Signal Peptide
DCLGFMRKCIPDADKCCRPNLVCSRTHKWCKYVF
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Disulfide Bond
2-17;9-23;16-30
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
190 nM
 . . [1]
 Target Info    Nav1.5 IC50
>5 μM
 . . [2]
 Target Info    Nav1.4 IC50
2.7 ± 0.2 μM
 . . [3]
References
Ref 1 Evaluation of Diverse Community Asthma Interventions: Balancing Health Outcomes with Developing Community Capacity for Evidence-Based Program Measurement. Popul Health Manag. 2015 Oct;18(5):342-50. doi: 10.1089/pop.2014.0144. Epub 2015 Feb 6.
Ref 2 Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for the rapid identification of yeasts causing bloodstream infections. Clin Microbiol Infect. 2015 Apr;21(4):372-8. doi: 10.1016/j.cmi.2014.11.009. Epub 2014 Nov 20.
Ref 3 Commentary on Cochrane review of neuraminidase inhibitors for preventing and treating influenza in healthy adults and children. Clin Microbiol Infect. 2015 Mar;21(3):217-21. doi: 10.1016/j.cmi.2014.10.011. Epub 2014 Oct 29.
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