Peptide Information

General Information of This Peptide
Peptide ID
BTDP000106
Peptide Name
GPTX1 (Arg7-Ala)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKYVF
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Mutant Sequence
DCLGFMAKCIPDNDKCCRPNLVCSRTHKWCKYVF
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Sequence Length
34
Mass(Da)
4081
Sequence Removed Signal Peptide
DCLGFMAKCIPDNDKCCRPNLVCSRTHKWCKYVF
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Disulfide Bond
2-17;9-23;16-30
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
940 nM
 . . [1]
 Target Info    Nav1.4 IC50
>4.6 μM
 . . [2]
 Target Info    Nav1.5 IC50
>5 μM
 . . [3]
References
Ref 1 Metabolomics of the bio-degradation process of aflatoxin B1 by actinomycetes at an initial pH of 6.0. Toxins (Basel). 2015 Feb 4;7(2):439-56. doi: 10.3390/toxins7020439.
Ref 2 High prevalence of human herpesvirus type 8 infection in patients with pulmonary tuberculosis in Taiwan. Clin Microbiol Infect. 2015 Mar;21(3):266.e5-7. doi: 10.1016/j.cmi.2014.10.015. Epub 2014 Oct 29.
Ref 3 Ticking the right boxes: classification of patients suspected of Lyme borreliosis at an academic referral center in the Netherlands. Clin Microbiol Infect. 2015 Apr;21(4):368.e11-20. doi: 10.1016/j.cmi.2014.11.014. Epub 2014 Nov 22.
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