General Information of This Peptide
Peptide ID
BTDP000100
Peptide Name
GPTX1 (Arg18Ala)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKYVF
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Mutant Sequence
DCLGFMRKCIPDNDKCCAPNLVCSRTHKWCKYVF
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Sequence Length
34
Mass(Da)
3996
Sequence Removed Signal Peptide
DCLGFMRKCIPDNDKCCAPNLVCSRTHKWCKYVF
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Disulfide Bond
2-17;9-23;16-30
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
130 nM
. . [1]
 Target Info    Nav1.5 IC50
>20 μM
. . [2]
 Target Info    Nav1.4 IC50
3.0 ± 0.6 μM
. . [3]
References
Ref 1 Changes to collagen structure during leather processing. J Agric Food Chem. 2015 Mar 11;63(9):2499-505. doi: 10.1021/jf506357j. Epub 2015 Feb 25.
Ref 2 Toscana virus meningitis case in Switzerland: an example of the ezVIR bioinformatics pipeline utility for the identification of emerging viruses. Clin Microbiol Infect. 2015 Apr;21(4):387.e1-4. doi: 10.1016/j.cmi.2014.11.010. Epub 2014 Nov 26.
Ref 3 Strong and persistent correlation between baseline and follow-up HIV-DNA levels and residual viremia in a population of na?ve patients with more than 4 years of effective antiretroviral therapy. Clin Microbiol Infect. 2015 Mar;21(3):288.e5-7. doi: 10.1016/j.cmi.2014.10.009. Epub 2014 Oct 29.
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