Target Information

General Information of This Target
Target ID
BTDT10306
Target Name
Voltage-gated potassium channel
Target Bioclass
Transporter and channel
Taxonomy ID
9606
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Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Potassium channel toxin alpha-KTx 15.1 Inhibition rate
25 %
 [1], [2]
References
Ref 1 Fast K(+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom. Biochim Biophys Acta. 2000 Sep 29;1468(1-2):203-12. doi: 10.1016/s0005-2736(00)00259-5.
Ref 2 A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K+ channels. Biochem Pharmacol. 2008 Sep 15;76(6):805-15. doi: 10.1016/j.bcp.2008.07.008. Epub 2008 Jul 18.
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