General Information of This Target
Target ID
BTDT10213
Target Name
Potassium voltage-gated channel subfamily H member 1
Target Bioclass
Transporter and channel
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N.A.
Species: Native protein
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Thrombin-like enzyme collinein-1 IC50
4.2 μM
[1], [2], [3], [4]
 Toxin Info    Thrombin-like enzyme collinein-1 IC50
4.2 μM
[1], [2], [3], [4]
 Toxin Info    Thrombin-like enzyme collinein-1 IC50
4.2 μM
[1], [2], [3], [4]
References
Ref 1 Expression of a new serine protease from Crotalus durissus collilineatus venom in Pichia pastoris and functional comparison with the native enzyme. Appl Microbiol Biotechnol. 2015 Dec;99(23):9971-86. doi: 10.1007/s00253-015-6836-2. Epub 2015 Jul 31.
Ref 2 Functional and biological insights of rCollinein-1, a recombinant serine protease from Crotalus durissus collilineatus. J Venom Anim Toxins Incl Trop Dis. 2019 Apr 8;25:e147118. doi: 10.1590/1678-9199-JVATITD-1471-18. eCollection 2019.
Ref 3 Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities. Sci Rep. 2020 Mar 11;10(1):4476. doi: 10.1038/s41598-020-61258-x.
Ref 4 Towards toxin PEGylation: The example of rCollinein-1, a snake venom thrombin-like enzyme, as a PEGylated biopharmaceutical prototype. Int J Biol Macromol. 2021 Nov 1;190:564-573. doi: 10.1016/j.ijbiomac.2021.09.004. Epub 2021 Sep 7.
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