Target Information

General Information of This Target
Target ID
BTDT10170
Target Name
Nicotinic acetylcholine receptor
Target Bioclass
Receptor
Taxonomy ID
9606
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Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Mu-theraphotoxin-Tp1a Inhibition rate . [1]
 Toxin Info    Three-finger toxin MS1 IC50
48.2 mM
 [2]
 Toxin Info    Short neurotoxin MS11 IC50
266 mM
 [2]
 Toxin Info    Three-finger toxin MS3 IC50
346 mM
 [2]
 Toxin Info    Long neurotoxin MS4 IC50
690 mM
 [2]
References
Ref 1 Identification and Characterization of ProTx-III [-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens. Mol Pharmacol. 2015 Aug;88(2):291-303. doi: 10.1124/mol.115.098178. Epub 2015 May 15.
Ref 2 Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny. Proteomics. 2008 May;8(9):1919-32. doi: 10.1002/pmic.200700668.
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