Target Information

General Information of This Target
Target ID
BTDT10079
Target Name
Muscarinic acetylcholine receptor M1;Muscarinic acetylcholine receptor M2
Target Bioclass
Receptor
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N.A.
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Adrenergic toxin rho-elapitoxin-Dp1a Inhibition constant
>1 μM
 [1], [2], [3], [4]
References
Ref 1 Muscarinic toxins from the black mamba Dendroaspis polylepis. Eur J Biochem. 1995 Dec 1;234(2):579-85. doi: 10.1111/j.1432-1033.1995.579_b.x.
Ref 2 Protein toxins that bind to muscarinic acetylcholine receptors. Ann N Y Acad Sci. 1994 Mar 9;710:153-61. doi: 10.1111/j.1749-6632.1994.tb26623.x.
Ref 3 Kinetic evidence for different mechanisms of interaction of black mamba toxins MT alpha and MT beta with muscarinic receptors. Toxicon. 2001 Feb-Mar;39(2-3):377-82. doi: 10.1016/s0041-0101(00)00141-0.
Ref 4 New -adrenergic property for synthetic MT and CM-3 three-finger fold toxins from black mamba. Toxicon. 2013 Dec 1;75:160-7. doi: 10.1016/j.toxicon.2013.04.017. Epub 2013 May 3.
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