Target Information

General Information of This Target
Target ID
BTDT10072
Target Name
KcsA-Kv1.6
Target Bioclass
Transporter and channel
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N.A.
Species: Chimera
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    AgTx2 Dissociation constant
1 nM
 [1]
 Toxin Info    Leiurotoxin-2 Kap
0.055 nM
 [1]
 Toxin Info    AgTx2 (H34A) Kap
0.3 nM
 [1]
 Toxin Info    MTX (GVPIN) Kap
0.35 nM
 [1]
 Toxin Info    OdK2 Kap
0.37 nM
 [1]
 Toxin Info    AgTx2 Inhibition rate . [2]
References
Ref 1 Complexes of Peptide Blockers with Kv1.6 Pore Domain: Molecular Modeling and Studies with KcsA-Kv1.6 Channel. J Neuroimmune Pharmacol. 2017 Jun;12(2):260-276. doi: 10.1007/s11481-016-9710-9. Epub 2016 Sep 17.
Ref 2 Atto488-Agitoxin 2-A Fluorescent Ligand with Increased Selectivity for Kv1.3 Channel Binding Site. Bioengineering (Basel). 2022 Jul 1;9(7):295. doi: 10.3390/bioengineering9070295.
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