Target Information

General Information of This Target
Target ID
BTDT10002
Target Name
5-hydroxytryptamine receptor 3A
Target Bioclass
Receptor
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N.A.
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Sigma-conotoxin GVIIIA IC50
53 - 86.8 nM
 [1], [2], [3]
References
Ref 1 Evolution of Conus peptide toxins: analysis of Conus californicus Reeve, 1844. Mol Phylogenet Evol. 2010 Jul;56(1):1-12. doi: 10.1016/j.ympev.2010.03.029. Epub 2010 Apr 2.
Ref 2 Inactivation of a serotonin-gated ion channel by a polypeptide toxin from marine snails. Science. 1998 Jul 24;281(5376):575-8. doi: 10.1126/science.281.5376.575.
Ref 3 S-conotoxin GVIIIB potently and selectively blocks 910 nicotinic acetylcholine receptors. Biochem Pharmacol. 2015 Aug 15;96(4):349-56. doi: 10.1016/j.bcp.2015.06.007. Epub 2015 Jun 11.
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