Peptide Information

General Information of This Peptide
Peptide ID
BTDP008952
Peptide Name
Kappa-hefutoxin 2 (Y2T,R3A,N4S,C5K,W6Q,R7C,E8W,G9P,N10V,D11C,E12N,E13Q,T14M,C15F,K16G,E17K,R18P,C19N)
Symonym
Kappa-hefutoxin 2 (Y2T,R3A,N4S,C5K,W6Q,R7C,E8W,G9P,N10V,D11C,E12N,E13Q,T14M,C15F,K16G,E17K,R18P,C19N)
3D Structure
Original Sequence
CYRNCWREGNDEETCKERC
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Mutant Sequence
CTASKQCWPVCNQMFGKPNGKCMNGKCRC
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Sequence Length
29
Mass(Da)
3218
Sequence Removed Signal Peptide
CTASKQCWPVCNQMFGKPNGKCMNGKCRC
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 Inhibition rate
4.6 %
1 μM
Blocker
 [1]
References
Ref 1 Different pharmacological properties between scorpion toxin BmKcug2 and its degraded analogs highlight the diversity of K(+) channel blockers from thermally processed scorpions. Int J Biol Macromol. 2021 May 1;178:143-153. doi: 10.1016/j.ijbiomac.2021.02.155. Epub 2021 Feb 23.
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