Peptide Information

General Information of This Peptide
Peptide ID
BTDP008935
Peptide Name
MTX (V1W,S2C,C3S,G5C,S6L,K7D,D8L,C9A,Y10C,A11T,P12G,C13S,R14K,K15D,Q16C,T17Y,G18A,C19P,P20C,N21R,A22K,K23Q,C24T,I25G,N26C,K27P,S28N,C29A,Y32I,G33N,C34K)
Symonym
MTX (V1W,S2C,C3S,G5C,S6L,K7D,D8L,C9A,Y10C,A11T,P12G,C13S,R14K,K15D,Q16C,T17Y,G18A,C19P,P20C,N21R,A22K,K23Q,C24T,I25G,N26C,K27P,S28N,C29A,Y32I,G33N,C34K)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
VSCTGSKDCYAPCRKQTGCPNAKCINKSCKCYGC
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Mutant Sequence
WCSTCLDLACTGSKDCYAPCRKQTGCPNAKCINKSCKCYGC
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Sequence Length
41
Mass(Da)
4419
Sequence Removed Signal Peptide
WCSTCLDLACTGSKDCYAPCRKQTGCPNAKCINKSCKCYGC
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    KCa3.1 IC50
2.2 nM
 .
Blocker
 [1]
References
Ref 1 Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity. Proteins. 2005 Aug 15;60(3):401-11. doi: 10.1002/prot.20509.
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