Peptide Information

General Information of This Peptide
Peptide ID
BTDP008915
Peptide Name
Discrepin
Symonym
Discrepin
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
QIDTNVKCSGSSKCVKICRKVYNTRGAKCINGRCTCYP
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Sequence Length
38
Mass (Da)
4176
Sequence Removed Signal Peptide
QIDTNVKCSGSSKCVKICRKVYNTRGAKCINGRCTCYP
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 IC50
764 nM
 .
Blocker
 [1]
References
Ref 1 A positive charge at the N-terminal segment of Discrepin increases the blocking effect of K+ channels responsible for the IA currents in cerebellum granular cells. Biochim Biophys Acta. 2008 Apr;1780(4):750-5. doi: 10.1016/j.bbagen.2008.01.012. Epub 2008 Jan 30.
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