General Information of This Peptide
Peptide ID
BTDP008881
Peptide Name
Toxin (3D,F4D,N6G,L7K,R8L,R9F,C10S,E11G,L12C,S13D,C14T,R15N,S16A,L17D,G18C,L19C,L20E,K22Y,C23V,I24C,G25R,E26L,E27W,C30L,V31D,P32W)
Symonym
Toxin (A3D,F4D,N6G,L7K,R8L,R9F,C10S,E11G,L12C,S13D,C14T,R15N,S16A,L17D,G18C,L19C,L20E,K22Y,C23V,I24C,G25R,E26L,E27W,C30L,V31D,P32W)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
DDCGKLFSGCDTNADCCEGYVCRLWCKLDW
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Mutant Sequence
GSDDCGKLFSGCDTNADCCEGYVCRLWCKLDW
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Sequence Length
32
Mass(Da)
3557
Sequence Removed Signal Peptide
GSDDCGKLFSGCDTNADCCEGYVCRLWCKLDW
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Disulfide Bond
5-19;12-24;18-28
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv2.1 Inhibition rate .
5 μM
Modifier
[1]
 Target Info    Kv1.4 Inhibition rate .
2 μM
Modifier
[1]
 Target Info    Kv4.1 Inhibition rate
30 %
2 μM
Modifier
[1]
References
Ref 1 Heteropoda toxin 2 is a gating modifier toxin specific for voltage-gated K+ channels of the Kv4 family. Toxicon. 2005 Mar 15;45(4):431-42. doi: 10.1016/j.toxicon.2004.11.015.
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