Peptide Information

General Information of This Peptide
Peptide ID
BTDP008857
Peptide Name
JZTX-V (S11A)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
YCQKWMWTCDSKRACCEGLRCKLWCRKII
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Mutant Sequence
YCQKWMWTCDAKRACCEGLRCKLWCRKII
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Sequence Length
29
Mass(Da)
3589
Sequence Removed Signal Peptide
YCQKWMWTCDAKRACCEGLRCKLWCRKII
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Disulfide Bond
2-16;9-21;15-25
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv4.2 IC50
10 nM
 .
Modifier
 [1]
References
Ref 1 JZTX-V Targets the Voltage Sensor in Kv4.2 to Inhibit I(to) Potassium Channels in Cardiomyocytes. Front Pharmacol. 2019 Apr 16;10:357. doi: 10.3389/fphar.2019.00357. eCollection 2019.
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