Peptide Information

General Information of This Peptide
Peptide ID
BTDP008753
Peptide Name
Venom basic protease inhibitor 1 homolog (N12D,K28A,K29A,K30G)
Symonym
Venom basic protease inhibitor 1 homolog (N12D,K28A,K29A,K30G)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
QPRRKLCILHRNPGRCYDKIPAFYYNQKKKQCERFDWSGCGGNSNRFKTIEECRRTCIG
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Mutant Sequence
QPRRKLCILHRDPGRCYDKIPAFYYNQKKKQCERFDWSGCGGNSNRFKTIEECRRTCIG
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Sequence Length
59
Mass(Da)
7066
Sequence Removed Signal Peptide
QPRRKLCILHRDPGRCYDKIPAFYYNQKKKQCERFDWSGCGGNSNRFKTIEECRRTCIG
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Disulfide Bond
7-40;16-53;32-57
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 Inhibition constant
0.22 nM
 .
Blocker
 [1]
 Target Info    Kv1 Inhibition constant
1.37 nM
 .
Blocker
 [1]
References
Ref 1 On the site by which alpha-dendrotoxin binds to voltage-dependent potassium channels: site-directed mutagenesis reveals that the lysine triplet 28-30 is not essential for binding. FEBS Lett. 1994 Dec 19;356(2-3):153-8. doi: 10.1016/0014-5793(94)01235-0.
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