Peptide Information

General Information of This Peptide
Peptide ID
BTDP008730
Peptide Name
Potassium channel toxin alpha-KTx 29.2
Symonym
Neurotoxin KTx3; Toxin LmKTx71
Species
Lychas mucronatus (Chinese swimming scorpion)
Uniprot Name
KA292_LYCMC
Alphafold ID
R4GUQ1
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: R4GUQ1
Sequence
MKSVCGVLIILVVLTTMLSISTFSTVGAEADCPISEAIKCVEKCKEKVEVCEPGVCKCSG
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Sequence Length
60
Mass (Da)
6282
Sequence Removed Signal Peptide
EADCPISEAIKCVEKCKEKVEVCEPGVCKCSG
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Disulfide Bond
32-51;40-56;44-58
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Lychas
Species: Lychas mucronatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 Inhibition rate
13 %
1 μM
Blocker
 [1]
 Target Info    Kv1.3 Inhibition rate
13.2 %
1 μM
Blocker
 [1]
 Target Info    Kv7.1 Inhibition rate
27 %
100 μM
Blocker
 [1]
 Target Info    Kv7.1 Inhibition rate
27.7 %
10 μM
Blocker
 [1]
References
Ref 1 Structural and functional diversity of acidic scorpion potassium channel toxins. PLoS One. 2012;7(4):e35154. doi: 10.1371/journal.pone.0035154. Epub 2012 Apr 12.
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