Peptide Information

General Information of This Peptide
Peptide ID
BTDP008673
Peptide Name
Potassium channel toxin gamma-KTx 3.1
Symonym
CnErgTx2; Ergtoxin-2; Ergtoxin-like protein
Species
Centruroides noxius (Mexican scorpion)
Uniprot Name
KGX31_CENNO
Alphafold ID
P59939
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P59939
Sequence
GRDSCVNKSRCAKYGYYSQCEVCCKKAGHKGGTCDFFKCKCKV
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Sequence Length
43
Mass (Da)
4791
Sequence Removed Signal Peptide
GRDSCVNKSRCAKYGYYSQCEVCCKKAGHKGGTCDFFKCKCKV
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Disulfide Bond
5-23;11-34;20-39;24-41
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Centruroides
Species: Centruroides noxius
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 IC50
418 nM
 .
Blocker
 [1], [2]
References
Ref 1 A large number of novel Ergtoxin-like genes and ERG K+-channels blocking peptides from scorpions of the genus Centruroides. FEBS Lett. 2002 Dec 4;532(1-2):121-6. doi: 10.1016/s0014-5793(02)03652-9.
Ref 2 Isolation of a long-lasting eag-related gene-type K+ current in MMQ lactotrophs and its accommodating role during slow firing and prolactin release. J Neurosci. 2002 May 1;22(9):3414-25. doi: 10.1523/JNEUROSCI.22-09-03414.2002.
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