Peptide Information

General Information of This Peptide
Peptide ID
BTDP008666
Peptide Name
Kappa-sparatoxin-Hv1c
Symonym
Heteropodatoxin-3; Toxin AU5C/KJ7
Species
Heteropoda venatoria (Brown huntsman spider) (Aranea venatoria)
Uniprot Name
TXHP3_HETVE
Alphafold ID
P58427
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P58427
Sequence
ECGTLFSGCSTHADCCEGFICKLWCRYERTW
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Sequence Length
31
Mass (Da)
3606
Sequence Removed Signal Peptide
ECGTLFSGCSTHADCCEGFICKLWCRYERTW
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Disulfide Bond
2-16;9-21;15-25
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Sparassidae
Genus: Heteropoda
Species: Heteropoda venatoria
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.4 Inhibition rate .
2 μM
Modifier
 [1]
 Target Info    Kv4.2 IC50
67 nM
 .
Modifier
 [1]
References
Ref 1 Heteropodatoxins: peptides isolated from spider venom that block Kv4.2 potassium channels. Mol Pharmacol. 1997 Mar;51(3):491-8.
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