Peptide Information

General Information of This Peptide
Peptide ID
BTDP008655
Peptide Name
Potassium channel toxin alpha-KTx 2.3
Symonym
C.1.limpidus toxin 1; Toxin II.10.9.1
Species
Centruroides limpidus (Mexican scorpion)
Uniprot Name
KAX23_CENLI
Alphafold ID
P45629
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P45629
Sequence
ITINVKCTSPQQCLRPCKDRFGQHAGGKCINGKCKCYP
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Sequence Length
38
Mass (Da)
4197
Sequence Removed Signal Peptide
ITINVKCTSPQQCLRPCKDRFGQHAGGKCINGKCKCYP
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Disulfide Bond
7-29;13-34;17-36
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Centruroides
Species: Centruroides limpidus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 Inhibition constant
0.1 nM
 .
Blocker
 [1], [2]
 Target Info    brain synaptosome Affinity
100 pM
 . . [1], [2]
References
Ref 1 Novel K(+)-channel-blocking toxins from the venom of the scorpion Centruroides limpidus limpidus Karsch. Biochem J. 1994 Nov 15;304 ( Pt 1)(Pt 1):51-6. doi: 10.1042/bj3040051.
Ref 2 Comparative proteomic analysis of female and male venoms from the Mexican scorpion Centruroides limpidus: Novel components found. Toxicon. 2017 Jan;125:91-98. doi: 10.1016/j.toxicon.2016.11.256. Epub 2016 Nov 24.
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