Peptide Information

General Information of This Peptide
Peptide ID
BTDP008646
Peptide Name
Omega-scoloptoxin(15)-Ssd3c
Symonym
Toxin SSD1052
Species
Scolopendra dehaani (Thai centipede) (Scolopendra subspinipes dehaani)
Uniprot Name
TXF3C_SCODE
Alphafold ID
P0DPT6
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: P0DPT6
Sequence
MEKKIIFLVVLVALLALPEFISSEVIKRDIPYKKRKFPYKSECLKACAAAFTGGDESRIQ
EGKPGFFKCTCYYTTG
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Sequence Length
76
Mass (Da)
8588
Sequence Removed Signal Peptide
EVIKRDIPYKKRKFPYKSECLKACAAAFTGGDESRIQEGKPGFFKCTCYYTTG
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        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Chilopoda
Order: Scolopendromorpha
Family: Scolopendridae
Genus: Scolopendra
Species: Scolopendra dehaani
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kir6.2 Dissociation constant
126 nM
 .
Blocker
 [1]
 Target Info    Kir6.2 Dissociation constant
278 nM
 .
Blocker
 [1]
 Target Info    Cav Increase rate
8.6 %
10 nM
Blocker
 [2]
References
Ref 1 A family of orthologous proteins from centipede venoms inhibit the hKir6.2 channel. Sci Rep. 2019 Oct 1;9(1):14088. doi: 10.1038/s41598-019-50688-x.
Ref 2 Venomic and transcriptomic analysis of centipede Scolopendra subspinipes dehaani. J Proteome Res. 2012 Dec 7;11(12):6197-212. doi: 10.1021/pr300881d. Epub 2012 Nov 29.
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