Peptide Information

General Information of This Peptide
Peptide ID
BTDP008639
Peptide Name
Scorpine-like peptide Ev37
Species
Euscorpiops validus (Scorpion)
Uniprot Name
KBX3_EUSVA
Alphafold ID
P0DL47
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0DL47
Sequence
MNSKLTVIVLLALITIASCGLINEKKVQQYLDEKLPNGVVKGALKSLVHKAAKNQNLCAF
NVDTVGMCDADCKRQGKAKGVCHGTKCKCDVELSYKK
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Sequence Length
97
Mass (Da)
10495
Signal Sequence
MNSKLTVIVLLALITIASC
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Sequence Removed Signal Peptide
GLINEKKVQQYLDEKLPNGVVKGALKSLVHKAAKNQNLCAFNVDTVGMCDADCKRQGKAK
GVCHGTKCKCDVELSYKK
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Disulfide Bond
58-82;68-87;72-89
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Euscorpiidae
Genus: Euscorpiops
Species: Euscorpiops validus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.1 Inhibition rate .
1 μM
Blocker
 [1]
 Target Info    Kv1.2 Inhibition rate .
1 μM
Blocker
 [1]
 Target Info    Kv1.3 IC50
950 nM
 .
Blocker
 [1]
 Target Info    Kv1.3 IC50
0.95 μM
 .
Blocker
 [1]
References
Ref 1 Expression and characterization of a novel scorpine-like peptide Ev37, from the scorpion Euscorpiops validus. Protein Expr Purif. 2013 Mar;88(1):127-33. doi: 10.1016/j.pep.2012.12.004. Epub 2012 Dec 20.
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