Peptide Information

General Information of This Peptide
Peptide ID
BTDP008581
Peptide Name
Potassium channel toxin alpha-KTx 16.7
Symonym
Alpha-KTx 16.5; MegKTx3
Species
Mesobuthus gibbosus (Mediterranean checkered scorpion) (Buthus gibbosus)
Uniprot Name
KA167_MESGB
Alphafold ID
B3EWY1
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: B3EWY1
Sequence
MKILSILLIALVICSISICTEAFGLIDVKCSASRECWVACKKVTGSGQGKCQNNQCRCY
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Sequence Length
59
Mass (Da)
6402
Sequence Removed Signal Peptide
FGLIDVKCSASRECWVACKKVTGSGQGKCQNNQCRCY
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Disulfide Bond
30-51;36-56;40-58
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Mesobuthus
Species: Mesobuthus gibbosus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 IC50
118 nM
 .
Blocker
 [1]
 Target Info    Kv1.3 IC50
118.3 ± 55.8 nM
 .
Blocker
 [1]
References
Ref 1 Novel potassium channel blocker venom peptides from Mesobuthus gibbosus (Scorpiones: Buthidae). Toxicon. 2013 Jan;61:72-82. doi: 10.1016/j.toxicon.2012.10.010. Epub 2012 Nov 7.
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