Peptide Information

General Information of This Peptide
Peptide ID
BTDP008580
Peptide Name
Kappa-buthitoxin-Tt2b
Species
Tityus trivittatus (Argentinean scorpion)
Uniprot Name
KA20X_TITTR
Alphafold ID
B3A0L5
3D Structure
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2D Sequence
3D Structure
Source
RSCB PDB: 2LI3
Sequence
GCMPEYCAGQCRGKVSQDYCLKNCRCIR
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Sequence Length
28
Mass (Da)
3186
Sequence Removed Signal Peptide
GCMPEYCAGQCRGKVSQDYCLKNCRCIR
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Disulfide Bond
2-24;7-20;11-26
PDB ID
2LI3
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Tityus
Species: Tityus trivittatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.2 Inhibition rate
75 %
2 mM
Blocker
 [1]
 Target Info    Shaker Inhibition rate
88 %
2 mM
Blocker
 [1]
References
Ref 1 New tricks of an old pattern: structural versatility of scorpion toxins with common cysteine spacing. J Biol Chem. 2012 Apr 6;287(15):12321-30. doi: 10.1074/jbc.M111.329607. Epub 2012 Jan 10.
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