Peptide Information

General Information of This Peptide
Peptide ID
BTDP008548
Peptide Name
Potassium channel toxin Tst-beta-KTx
Symonym
TstbetaKTx
Species
Tityus stigmurus (Brazilian scorpion)
Uniprot Name
KBX1_TITST
Alphafold ID
P0C2F3
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0C2F3
Sequence
KLVALIPNDQLRSILKAVVHKVAKTQFGCPAYEGYCNDHCNDIERKDGECHGFKCKCAKD
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Sequence Length
60
Mass (Da)
6723
Sequence Removed Signal Peptide
KLVALIPNDQLRSILKAVVHKVAKTQFGCPAYEGYCNDHCNDIERKDGECHGFKCKCAKD
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Disulfide Bond
29-50;36-55;40-57
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Tityus
Species: Tityus stigmurus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 IC50
96 nM
 .
Blocker
 [1], [2], [3]
References
Ref 1 Proteomic analysis of the venom from the scorpion Tityus stigmurus: biochemical and physiological comparison with other Tityus species. Comp Biochem Physiol C Toxicol Pharmacol. 2007 Jul-Aug;146(1-2):147-157. doi: 10.1016/j.cbpc.2006.12.004. Epub 2006 Dec 16.
Ref 2 Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components. Peptides. 2007 Jan;28(1):31-7. doi: 10.1016/j.peptides.2006.06.012. Epub 2006 Dec 1.
Ref 3 Cytolytic and K+ channel blocking activities of beta-KTx and scorpine-like peptides purified from scorpion venoms. Cell Mol Life Sci. 2008 Jan;65(1):187-200. doi: 10.1007/s00018-007-7370-x.
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