Peptide Information

General Information of This Peptide
Peptide ID
BTDP008521
Peptide Name
Potassium channel toxin alpha-KTx 8.7
Symonym
Toxin MeKTx1-2
Species
Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)
Uniprot Name
KAX87_MESEU
Alphafold ID
C0HJQ5
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: C0HJQ5
Sequence
MSRLYAIILIALVFNVIMTIMPDMKVEAVSCEDCPPHCATKDQRAKCENDKCVCEPK
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Sequence Length
57
Mass (Da)
6417
Sequence Removed Signal Peptide
MSRLYAIILIALVFNVIMTIMPDMKVEAVSCEDCPPHCATKDQRAKCENDKCVCEPK
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Disulfide Bond
31-47;34-52;38-54
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Mesobuthus
Species: Mesobuthus eupeus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 IC50
8.5 nM
 .
Blocker
 [1]
 Target Info    Kv1 IC50
8.5 nM
 .
Blocker
 [1]
References
Ref 1 Variability of Potassium Channel Blockers in Mesobuthus eupeus Scorpion Venom with Focus on Kv1.1: AN INTEGRATED TRANSCRIPTOMIC AND PROTEOMIC STUDY. J Biol Chem. 2015 May 8;290(19):12195-209. doi: 10.1074/jbc.M115.637611. Epub 2015 Mar 19.
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