Peptide Information

General Information of This Peptide
Peptide ID
BTDP008476
Peptide Name
Potassium channel toxin alpha-KTx 2.11
Symonym
Toxin Ce4
Species
Centruroides elegans (Bark scorpion)
Uniprot Name
KAX2B_CENEL
Alphafold ID
P0C164
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0C164
Sequence
TIINVKCTSPKQCLLPCKEIYGIHAGAKCMNGKCKCYKI
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Sequence Length
39
Mass (Da)
4302
Sequence Removed Signal Peptide
TIINVKCTSPKQCLLPCKEIYGIHAGAKCMNGKCKCYKI
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Disulfide Bond
7-29;13-34;17-36
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Centruroides
Species: Centruroides elegans
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 Dissociation constant
0.98 nM
 .
Blocker
 [1]
 Target Info    Kv1.3 Dissociation constant
0.98 nM
 .
Blocker
 [1]
References
Ref 1 Novel alpha-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockade Kv1.3 over IKCa1 K+ channels of T cells. Toxicon. 2005 Sep 15;46(4):418-29. doi: 10.1016/j.toxicon.2005.06.001.
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