Peptide Information

General Information of This Peptide
Peptide ID
BTDP008439
Peptide Name
Pi-phymatoxin-Pcf1a
Symonym
Pi-PMTX-Pcr1a; Toxin PhcrTx1
Species
Phymanthus crucifer (Red beaded anemone)
Uniprot Name
TXPM1_PHYCF
Alphafold ID
C0HJB1
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: C0HJB1
Sequence
CASQGQKCKTKSDCCNGMWCAGTRGHTCYKPK
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Sequence Length
32
Mass (Da)
3482
Sequence Removed Signal Peptide
CASQGQKCKTKSDCCNGMWCAGTRGHTCYKPK
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Disulfide Bond
1-15;8-20;14-28
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Kingdom: Metazoa
Phylum: Cnidaria
Class: Anthozoa
Order: Actiniaria
Family: Phymanthidae
Genus: Phymanthus
Species: Phymanthus crucifer
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    acid-sensing ion channel (ASIC) IC50
100 nM
 .
Blocker
 [1]
 Target Info    Kv1 IC50
3.5 μM
 .
Blocker
 [1]
 Target Info    Kv IC50
3.5 μM
 .
Blocker
 [1]
References
Ref 1 A novel sea anemone peptide that inhibits acid-sensing ion channels. Peptides. 2014 Mar;53:3-12. doi: 10.1016/j.peptides.2013.06.003. Epub 2013 Jun 10.
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