Peptide Information

General Information of This Peptide
Peptide ID
BTDP008400
Peptide Name
Kappa-theraphotoxin-Tb1a
Symonym
Theraphotoxin-1; TlTx1
Species
Theraphosa blondi (Goliath birdeating spider)
Uniprot Name
TX1_THEBL
Alphafold ID
P83745
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P83745
Sequence
AACLGMFESCDPNNDKCCPNRECNRKHKWCKYKLW
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Sequence Length
35
Mass (Da)
4193
Sequence Removed Signal Peptide
AACLGMFESCDPNNDKCCPNRECNRKHKWCKYKLW
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Disulfide Bond
3-18;10-23;17-30
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Theraphosidae
Genus: Theraphosa
Species: Theraphosa blondi
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv4.2 IC50
193 nM
 .
Modifier
 [1], [2]
 Target Info    Kv4.2 IC50
193 nM
 .
Modifier
 [1], [2]
References
Ref 1 Nanospray analysis of the venom of the tarantula Theraphosa leblondi: a powerful method for direct venom mass fingerprinting and toxin sequencing. Rapid Commun Mass Spectrom. 2004;18(10):1024-32. doi: 10.1002/rcm.1442.
Ref 2 Modulation of Kv4.2 channels by a peptide isolated from the venom of the giant bird-eating tarantula Theraphosa leblondi. Toxicon. 2004 Jun 15;43(8):923-32. doi: 10.1016/j.toxicon.2003.12.012.
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