Peptide Information

General Information of This Peptide
Peptide ID
BTDP008386
Peptide Name
KappaPI-stichotoxin-Shd2a
Symonym
Kunitz-type protease inhibitor and potassium channel toxin SHTX III; Kunitz-type protease inhibitor and potassium channel toxin SHTX-3
Species
Stichodactyla haddoni (Saddle carpet anemone) (Haddon's sea anemone)
Uniprot Name
VKT3_STIHA
Alphafold ID
B1B5I8
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: B1B5I8
Sequence
MAKLYFLLCLALVACLTMATEEMPALCHLQPDVPKCRGYFPRYYYNPEVGKCEQFIYGGC
GGNKNNFVSFEACRATCIIPL
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Sequence Length
81
Mass (Da)
9111
Signal Sequence
MAKLYFLLCLALVACLTMA
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Sequence Removed Signal Peptide
TEEMPALCHLQPDVPKCRGYFPRYYYNPEVGKCEQFIYGGCGGNKNNFVSFEACRATCII
PL
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Disulfide Bond
27-77;36-60;52-73
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Kingdom: Metazoa
Phylum: Cnidaria
Class: Anthozoa
Order: Actiniaria
Family: Stichodactylidae
Genus: Stichodactyla
Species: Stichodactyla haddoni
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 IC50
650 nM
 . . [1], [2]
References
Ref 1 Novel peptide toxins from the sea anemone Stichodactyla haddoni. Peptides. 2008 Apr;29(4):536-44. doi: 10.1016/j.peptides.2007.12.010. Epub 2008 Feb 19.
Ref 2 Development of a rational nomenclature for naming peptide and protein toxins from sea anemones. Toxicon. 2012 Sep 15;60(4):539-50. doi: 10.1016/j.toxicon.2012.05.020. Epub 2012 Jun 5.
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