Peptide Information

General Information of This Peptide
Peptide ID
BTDP008374
Peptide Name
Kappa-actitoxin-Avd6a
Symonym
Kaliseptine
Species
Anemonia sulcata (Mediterranean snakelocks sea anemone)
Uniprot Name
K1B_ANESU
Alphafold ID
Q9TWG1
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: Q9TWG1
Sequence
ACKDNFAAATCKHVKENKNCGSQKYATNCAKTCGKC
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Sequence Length
36
Mass (Da)
3840
Sequence Removed Signal Peptide
ACKDNFAAATCKHVKENKNCGSQKYATNCAKTCGKC
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Disulfide Bond
2-36;11-29;20-33
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Kingdom: Metazoa
Phylum: Cnidaria
Class: Anthozoa
Order: Actiniaria
Family: Actiniidae
Genus: Anemonia
Species: Anemonia sulcata
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.2 IC50
140 nM
 . . [1], [2]
 Target Info    Kv1.2 IC50
140 nM
 . . [1], [2]
References
Ref 1 Kalicludines and kaliseptine. Two different classes of sea anemone toxins for voltage sensitive K+ channels. J Biol Chem. 1995 Oct 20;270(42):25121-6. doi: 10.1074/jbc.270.42.25121.
Ref 2 Development of a rational nomenclature for naming peptide and protein toxins from sea anemones. Toxicon. 2012 Sep 15;60(4):539-50. doi: 10.1016/j.toxicon.2012.05.020. Epub 2012 Jun 5.
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