Peptide Information

General Information of This Peptide
Peptide ID
BTDP008347
Peptide Name
Basic phospholipase A2 homolog Gln49-PLA2
Symonym
svPLA2 homolog
Species
Gloydius ussuriensis (Ussuri mamushi) (Gloydius blomhoffii ussuriensis)
Uniprot Name
PA2H_GLOUS
Alphafold ID
P0DKU1
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: P0DKU1
Sequence
SLLQFRKMIKKMTGKEPVVSYAFYGCYCGSGGRGKPKDATDRCCFVHQCCYEKVTGCDPK
WDDYTYSWKDGDIVCGGDDPCKKEVCECDRAAAICFRDNLKTYKKIYMAYPDIFCSSKSE
KC
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Sequence Length
122
Mass (Da)
13896
Sequence Removed Signal Peptide
SLLQFRKMIKKMTGKEPVVSYAFYGCYCGSGGRGKPKDATDRCCFVHQCCYEKVTGCDPK
WDDYTYSWKDGDIVCGGDDPCKKEVCECDRAAAICFRDNLKTYKKIYMAYPDIFCSSKSE
KC
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Disulfide Bond
26-115;28-44;43-95;49-122;50-88;57-81;75-86
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Viperidae
Genus: Gloydius
Species: Gloydius ussuriensis
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 Inhibition rate
54.25 %
20 μM
 . [1], [2], [3]
References
Ref 1 Purification, characterization and gene cloning of a novel phospholipase A2 from the venom of Agkistrodon blomhoffii ussurensis. Int J Biochem Cell Biol. 2005 Mar;37(3):558-65. doi: 10.1016/j.biocel.2004.05.022.
Ref 2 Neurotoxic activity of Gln49 phospholipase A(2) from Gloydius ussuriensis snake venom. J Appl Toxicol. 2007 Sep-Oct;27(5):447-52. doi: 10.1002/jat.1222.
Ref 3 Mechanisms of analgesic action of Gln49-PLA(2) from Gloydius ussurensis snake venom. Appl Biochem Biotechnol. 2010 Mar;160(3):773-9. doi: 10.1007/s12010-009-8573-4. Epub 2009 Mar 10.
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