Peptide Information

General Information of This Peptide
Peptide ID
BTDP008346
Peptide Name
Acidic phospholipase A2 natratoxin
Symonym
Phosphatidylcholine 2-acylhydrolase
Species
Naja atra (Chinese cobra)
Uniprot Name
PA2A_NAJAT
Alphafold ID
A4FS04
3D Structure
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2D Sequence
3D Structure
Source
RSCB PDB: 2OSH
Sequence
NLYQFKNMIQCTVPSRSWWDFADYGCYCGKGGSGTPVDDLDRCCQVHDNCYNEAEKISGC
WPYFKTYSYECSQGTLTCKGGNNACAAAVCDCDRLAAICFAGAPYTDANYNIDLKARCQ
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Sequence Length
119
Mass (Da)
13188
Sequence Removed Signal Peptide
NLYQFKNMIQCTVPSRSWWDFADYGCYCGKGGSGTPVDDLDRCCQVHDNCYNEAEKISGC
WPYFKTYSYECSQGTLTCKGGNNACAAAVCDCDRLAAICFAGAPYTDANYNIDLKARCQ
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Disulfide Bond
11-71;26-118;28-44;43-99;50-92;60-85;78-90
PDB ID
2OSH
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Elapidae
Genus: Naja
Species: Naja atra
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 Inhibition rate
57 %
100 μM
 . [1]
References
Ref 1 Crystal structure of Natratoxin, a novel snake secreted phospholipaseA2 neurotoxin from Naja atra venom inhibiting A-type K+ currents. Proteins. 2008 Aug;72(2):673-83. doi: 10.1002/prot.21964.
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