Peptide Information

General Information of This Peptide
Peptide ID
BTDP008221
Peptide Name
Precursor protein UG
Species
Urticina grebelnyi (Painted anemone)
Uniprot Name
TX9A_URTGR
Alphafold ID
R4ZCU1
3D Structure
Download
2D Sequence
3D Structure
Source
RSCB PDB: 2LZO
Sequence
MERILLCFIVATLVAISMANPRPISIDPPCWTCYYRDSSGNCAFDAIACGGARKRVPKPI
SIDPPCRTCYYRDSSGNCVYDAFGCGGARKRVPKPISIDPPCRTCYYRDSSGNCVYDAFG
CGGARKRVPKPISIDPPCRFCYHRDGSGNCVYDAYGCGAVRK
   Click to Show/Hide
Sequence Length
162
Mass (Da)
17737
Signal Sequence
MERILLCFIVATLVAISMA
   Click to Show/Hide
Sequence Removed Signal Peptide
NPRPISIDPPCWTCYYRDSSGNCAFDAIACGGARKRVPKPISIDPPCRTCYYRDSSGNCV
YDAFGCGGARKRVPKPISIDPPCRTCYYRDSSGNCVYDAFGCGGARKRVPKPISIDPPCR
FCYHRDGSGNCVYDAYGCGAVRK
   Click to Show/Hide
Disulfide Bond
30-42;33-49;66-78;69-85;102-114;105-121;138-150;141-157
PDB ID
2LZO
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Cnidaria
Class: Anthozoa
Order: Actiniaria
Family: Actiniidae
Genus: Urticina
Species: Urticina grebelnyi
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 Inhibition rate .
1 μM
Pi-actitoxin-Ugr1a
 [1]
 Target Info    ASIC1a Inhibition rate .
50 μM
Pi-actitoxin-Ugr1a
 [1]
 Target Info    ASIC2a/ASIC2 Inhibition rate .
50 μM
Pi-actitoxin-Ugr1a
 [1]
 Target Info    ASIC3 IC50
1.44 μM
 .
Pi-actitoxin-Ugr1a
 [1]
 Target Info    ASIC3 IC50
10 μM
 .
Pi-actitoxin-Ugr1a
 [1]
References
Ref 1 Sea anemone peptide with uncommon -hairpin structure inhibits acid-sensing ion channel 3 (ASIC3) and reveals analgesic activity. J Biol Chem. 2013 Aug 9;288(32):23116-27. doi: 10.1074/jbc.M113.485516. Epub 2013 Jun 25.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.