Peptide Information

General Information of This Peptide
Peptide ID
BTDP006817
Peptide Name
Sodium channel neurotoxin MeuNaTxalpha-5
Species
Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)
Uniprot Name
SCXN5_MESEU
Alphafold ID
P86405
3D Structure
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2D Sequence
3D Structure
Source
RSCB PDB: 2LKB
Sequence
MNYLILISFALLVITGVESARDAYIAKPHNCVYECFDAFSSYCNGVCTKNGAKSGYCQIL
GTYGNGCWCIALPDNVPIRIPGKCHR
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Sequence Length
86
Mass (Da)
9414
Signal Sequence
MNYLILISFALLVITGVES
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Sequence Removed Signal Peptide
ARDAYIAKPHNCVYECFDAFSSYCNGVCTKNGAKSGYCQILGTYGNGCWCIALPDNVPIR
IPGKCHR
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Disulfide Bond
31-84;35-57;43-67;47-69
PDB ID
2LKB
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Mesobuthus
Species: Mesobuthus eupeus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Para/DmNav1 Effective concentration 50
280 nM
 . . [1]
 Target Info    Nav1.6 Effective concentration 50
790 nM
 . . [1]
References
Ref 1 Evolutionary diversification of Mesobuthus -scorpion toxins affecting sodium channels. Mol Cell Proteomics. 2012 Jan;11(1):M111.012054. doi: 10.1074/mcp.M111.012054. Epub 2011 Oct 3.
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