Peptide Information

General Information of This Peptide
Peptide ID
BTDP006739
Peptide Name
Oxiana weak toxin
Symonym
OWT
Species
Naja oxiana (Central Asian cobra) (Oxus cobra)
Uniprot Name
3NO2_NAJOX
Alphafold ID
P85520
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P85520
Sequence
LTCLICPEKYCNKVHTCRNGEKICFKKFDQRKLLGKRYIRGCAATCPEAKPREIVECCST
DKCNH
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Sequence Length
65
Mass (Da)
7496
Sequence Removed Signal Peptide
LTCLICPEKYCNKVHTCRNGEKICFKKFDQRKLLGKRYIRGCAATCPEAKPREIVECCST
DKCNH
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Disulfide Bond
3-24;6-11;17-42;46-57;58-63
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Elapidae
Genus: Naja
Species: Naja oxiana
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-7 IC50
2.2 μM
 . . [1], [2]
 Target Info    membranes IC50
30 μM
 . . [1], [2]
References
Ref 1 [New weak toxins from the cobra venom]. Bioorg Khim. 2009 Jan-Feb;35(1):15-24. doi: 10.1134/s1068162009010026.
Ref 2 Neurotoxins from snake venoms and -conotoxin ImI inhibit functionally active ionotropic -aminobutyric acid (GABA) receptors. J Biol Chem. 2015 Sep 11;290(37):22747-58. doi: 10.1074/jbc.M115.648824. Epub 2015 Jul 28.
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