Peptide Information

General Information of This Peptide
Peptide ID
BTDP006531
Peptide Name
Neurotoxin Oh9-1
Symonym
OMEGA-neurotoxin Oh9-1; Three-finger toxin
Species
Ophiophagus hannah (King cobra) (Naja hannah)
Uniprot Name
3SX1_OPHHA
Alphafold ID
P83302
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: P83302
Sequence
LICHRVHGLQTCEPDQKFCFRKTTMFFPNHPVLLMGCTSSCPTEKYSVCCSTDKCNK
   Click to Show/Hide
Sequence Length
57
Mass (Da)
6516
Sequence Removed Signal Peptide
LICHRVHGLQTCEPDQKFCFRKTTMFFPNHPVLLMGCTSSCPTEKYSVCCSTDKCNK
   Click to Show/Hide
Disulfide Bond
3-19;12-37;41-49;50-55
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Elapidae
Genus: Ophiophagus
Species: Ophiophagus hannah
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-1-beta-1-delta-epsilon IC50
3.1 μM
 . . [1], [2]
 Target Info    nAChR alpha-1-beta-1-gamma-delta IC50
5.6 μM
 .
Fetal subtype
 [1], [2]
 Target Info    nAChR alpha-3-beta-2 IC50
50.2 μM
 . . [1], [2]
References
Ref 1 Purification and characterization of a neurotoxin from the venom of Ophiophagus hannah (king cobra). Biochem Biophys Res Commun. 2002 Jun 14;294(3):574-8. doi: 10.1016/S0006-291X(02)00518-1.
Ref 2 A Distinct Functional Site in -Neurotoxins: Novel Antagonists of Nicotinic Acetylcholine Receptors from Snake Venom. ACS Chem Biol. 2015 Dec 18;10(12):2805-15. doi: 10.1021/acschembio.5b00492. Epub 2015 Oct 15.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.