Peptide Information

General Information of This Peptide
Peptide ID
BTDP005763
Peptide Name
Kappa-2-bungarotoxin
Symonym
Kappa-neurotoxin CB1
Species
Bungarus multicinctus (Many-banded krait)
Uniprot Name
3LK2_BUNMU
Alphafold ID
P15816
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P15816
Sequence
MKTLLLTLVVVTIVCLDLGYTKTCLKTPSSTPQTCPQGQDICFLKVSCEQFCPIRGPVIE
QGCAATCPEFRSNDRSLLCCTTDNCNH
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Sequence Length
87
Mass (Da)
9517
Signal Sequence
MKTLLLTLVVVTIVCLDLGYT
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Sequence Removed Signal Peptide
KTCLKTPSSTPQTCPQGQDICFLKVSCEQFCPIRGPVIEQGCAATCPEFRSNDRSLLCCT
TDNCNH
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Disulfide Bond
24-42;35-63;48-52;67-79;80-85
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Elapidae
Genus: Bungarus
Species: Bungarus multicinctus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR IC50
<100 nM
 . . [1], [2]
References
Ref 1 cDNA deduced amino-acid sequences of two novel kappa-neurotoxins from Bungarus multicinctus. Nucleic Acids Res. 1990 Feb 25;18(4):1050. doi: 10.1093/nar/18.4.1050.
Ref 2 Kappa 2-bungarotoxin and kappa 3-bungarotoxin: two new neuronal nicotinic receptor antagonists isolated from the venom of Bungarus multicinctus. Brain Res. 1990 Feb 19;509(2):237-48. doi: 10.1016/0006-8993(90)90548-p.
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