General Information of This Peptide
Peptide ID
BTDP005762
Peptide Name
Kappa-flavitoxin
Symonym
Long neurotoxin 2
Species
Bungarus flaviceps flaviceps (Red-headed krait)
Uniprot Name
3LKF_BUNFL
Alphafold ID
P15815
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P15815
Sequence
RTCLISPSSTSQTCPKGQDICFTKAFCDRWCSSRGPVIEQGCAATCPEFTSRYKSLLCCT
TDNCNH
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Sequence Length
66
Mass (Da)
7259
Sequence Removed Signal Peptide
RTCLISPSSTSQTCPKGQDICFTKAFCDRWCSSRGPVIEQGCAATCPEFTSRYKSLLCCT
TDNCNH
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Disulfide Bond
3-21;14-42;27-31;46-58;59-64
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Elapidae
Genus: Bungarus
Species: Bungarus flaviceps
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR IC50
<100 nM
. . [1], [2], [3]
References
Ref 1 Amino acid sequence of kappa-flavitoxin: establishment of a new family of snake venom neurotoxins. Biochemistry. 1988 May 17;27(10):3794-8. doi: 10.1021/bi00410a041.
Ref 2 Kappa-flavitoxin: isolation of a new neuronal nicotinic receptor antagonist that is structurally related to kappa-bungarotoxin. Brain Res. 1987 Jan 27;402(1):21-9. doi: 10.1016/0006-8993(87)91043-2.
Ref 3 Homologous kappa-neurotoxins exhibit residue-specific interactions with the alpha 3 subunit of the nicotinic acetylcholine receptor: a comparison of the structural requirements for kappa-bungarotoxin and kappa-flavitoxin binding. Biochemistry. 1993 Jul 13;32(27):6988-94. doi: 10.1021/bi00078a025.
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