Peptide Information

General Information of This Peptide
Peptide ID
BTDP005693
Peptide Name
Conotoxin FVIA
Species
Conus fulmen (Thunderbolt cone) (Chelyconus fulmen)
Uniprot Name
O16A_CONFU
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
ILSLSLLDRSTRCKGTGKSCSRIAYNCCTGSCRSGKCG
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Sequence Length
38
Mass (Da)
3987
Sequence Removed Signal Peptide
ILSLSLLDRSTRCKGTGKSCSRIAYNCCTGSCRSGKCG
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Disulfide Bond
13-28;20-32;27-37
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus fulmen
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Cav2.2 IC50
11.5 nM
 . . [1]
References
Ref 1 Analgesic effect of highly reversible -conotoxin FVIA on N type Ca2+ channels. Mol Pain. 2010 Dec 21;6:97. doi: 10.1186/1744-8069-6-97.
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