Peptide Information

General Information of This Peptide
Peptide ID
BTDP005643
Peptide Name
FMRFamide-like peptide Sa12b
Symonym
Sa-112
Species
Sphex argentatus argentatus (Black digger wasp)
Uniprot Name
FLP12_SPHAA
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
EDVDHVFLRF
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Sequence Length
10
Mass (Da)
1276
Sequence Removed Signal Peptide
EDVDHVFLRF
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        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Insecta
Order: Hymenoptera
Family: Sphecidae
Genus: Sphex
Species: Sphex argentatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    DRG neuron IC50
81 nM
 .
Inhibit both the frequency and amplitude of spontaneous contractions of the locust oviducts
 [1], [2], [3]
References
Ref 1 Sa12b Peptide from Solitary Wasp Inhibits ASIC Currents in Rat Dorsal Root Ganglion Neurons. Toxins (Basel). 2019 Oct 10;11(10):585. doi: 10.3390/toxins11100585.
Ref 2 Isolation and characterization of FMRFamide-like peptides in the venoms of solitary sphecid wasps. Peptides. 2021 Aug;142:170575. doi: 10.1016/j.peptides.2021.170575. Epub 2021 May 20.
Ref 3 Peptide Toxins in Solitary Wasp Venoms. Toxins (Basel). 2016 Apr 18;8(4):114. doi: 10.3390/toxins8040114.
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