Peptide Information

General Information of This Peptide
Peptide ID
BTDP005374
Peptide Name
Mu-theraphotoxin-Hsp1a
Symonym
Hsp1a; Mu-TRTX-Hsp1a
Species
Homoeomma sp. (Peruvian tarantula)
Uniprot Name
PM1A_HOMSP
Alphafold ID
P0DQO2
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0DQO2
Sequence
YCQKFLWTCDSERPCCEGLVCRLWCKIN
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Sequence Length
28
Mass (Da)
3398
Sequence Removed Signal Peptide
YCQKFLWTCDSERPCCEGLVCRLWCKIN
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Disulfide Bond
2-16;9-21;15-25
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Theraphosidae
Genus: Homoeomma
Species: Homoeomma sp.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
13 nM
 . . [1]
References
Ref 1 Fluorescence Imaging of Peripheral Nerves by a Na(v)1.7-Targeted Inhibitor Cystine Knot Peptide. Bioconjug Chem. 2019 Nov 20;30(11):2879-2888. doi: 10.1021/acs.bioconjchem.9b00612. Epub 2019 Nov 8.
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