Peptide Information

General Information of This Peptide
Peptide ID
BTDP005177
Peptide Name
Mu-theraphotoxin-Df1a
Symonym
Mu-TRTX-Df1a
Species
Davus fasciatus (Costa Rican tiger rump) (Cyclosternum fasciatus)
Uniprot Name
TXDF1_DAFVA
Alphafold ID
P0DPC2
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0DPC2
Sequence
ECRWFLGGCSGGQTCCEHLVCHRKHQWCVWDWSF
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Sequence Length
34
Mass (Da)
4086
Sequence Removed Signal Peptide
ECRWFLGGCSGGQTCCEHLVCHRKHQWCVWDWSF
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Disulfide Bond
2-16;9-21;15-28
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Theraphosidae
Genus: Davus
Species: Davus fasciatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
117 nM
 . . [1]
References
Ref 1 Modulatory features of the novel spider toxin -TRTX-Df1a isolated from the venom of the spider Davus fasciatus. Br J Pharmacol. 2017 Aug;174(15):2528-2544. doi: 10.1111/bph.13865. Epub 2017 Jun 27.
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