Peptide Information

General Information of This Peptide
Peptide ID
BTDP004942
Peptide Name
Voltage sensor toxin 3
Symonym
Beta/kappa-theraphotoxin-Gr4a
Species
Paraphysa scrofa (Chilean copper tarantula) (Phrixotrichus auratus)
Uniprot Name
VSTX3_PARSR
Alphafold ID
P0DL74
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0DL74
Sequence
DCLGWFKGCDPDNDKCCEGYKCNRRDKWCKYKLW
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Sequence Length
34
Mass (Da)
4178
Sequence Removed Signal Peptide
DCLGWFKGCDPDNDKCCEGYKCNRRDKWCKYKLW
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Disulfide Bond
2-17;9-22;16-29
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Theraphosidae
Genus: Paraphysa
Species: Paraphysa scrofa
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.3 IC50
190 nM
 . . [1]
 Target Info    Nav1.3 IC50
210 nM
 . . [1]
 Target Info    Nav1.8 IC50
290 nM
 . . [1]
 Target Info    Nav1.7 IC50
430 nM
 . . [1]
 Target Info    Nav1.8 IC50
770 nM
 . . [1]
References
Ref 1 Two tarantula venom peptides as potent and differential Na(V) channels blockers. Toxicon. 2014 Jan;77:58-67. doi: 10.1016/j.toxicon.2013.10.029. Epub 2013 Nov 7.
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