Peptide Information

General Information of This Peptide
Peptide ID
BTDP004517
Peptide Name
Conopeptide-Ac1
Symonym
5P1; 5P2; Conopeptide Ac3.1; Conotoxin-Ac1; Conotoxin-Ac1-O6P
Species
Conus achatinus (Little frog cone)
Uniprot Name
CA1_CONAH
Alphafold ID
P0CH24
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0CH24
Sequence
LGVLVTIFLVLFPMATLQLDGDQTADRHAGERDQDPLEQYRNLKHVLRRTRNYYLYPARP
ENSWWT
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Sequence Length
66
Mass (Da)
7860
Signal Sequence
LGVLVTIFLVLFPMATLQLDG
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Sequence Removed Signal Peptide
DQTADRHAGERDQDPLEQYRNLKHVLRRTRNYYLYPARPENSWWT
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        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus achatinus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    NR2B IC50
8.22 μM
 . . [1], [2]
References
Ref 1 Novel conopeptides in a form of disulfide-crosslinked dimer. Peptides. 2010 Jun;31(6):1001-6. doi: 10.1016/j.peptides.2010.03.010. Epub 2010 Mar 20.
Ref 2 Structural and Functional Characterization of Conotoxins from Conus achatinus Targeting NMDAR. Mar Drugs. 2020 Feb 26;18(3):135. doi: 10.3390/md18030135.
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