Peptide Information

General Information of This Peptide
Peptide ID
BTDP004089
Peptide Name
Alpha-conotoxin PeIVA
Species
Conus pergrandis (Grand cone)
Uniprot Name
CA4A_CONPR
Alphafold ID
P0C1W9
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0C1W9
Sequence
CCGVPNAACHPCVCTGKC
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Sequence Length
18
Mass (Da)
1766
Sequence Removed Signal Peptide
CCGVPNAACHPCVCTGKC
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        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus pergrandis
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-1-beta-1-gamma-delta IC50
≤5 nM
 . . [1]
 Target Info    nAChR alpha-1-beta-1-epsilon-delta IC50
4 μM
 . . [1]
References
Ref 1 Definition and characterization of the short alphaA-conotoxins: a single residue determines dissociation kinetics from the fetal muscle nicotinic acetylcholine receptor. Biochemistry. 2006 Jan 31;45(4):1304-12. doi: 10.1021/bi052016d.
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