Peptide Information

General Information of This Peptide
Peptide ID
BTDP003725
Peptide Name
Three-finger toxin A1
Symonym
Short chain alpha-neurotoxin A1
Species
Micrurus laticollaris (Balsas coral snake)
Uniprot Name
3S11_MICLL
Alphafold ID
K9MCH1
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: K9MCH1
Sequence
MKTLLLTLVVVTIVCLDFGHTRICYNQQSSQPPTTKTCSEGQCYKKTWRDHRGTIIERGC
ACPNVKPGIQISCCTSDKCNG
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Sequence Length
81
Mass (Da)
8980
Signal Sequence
MKTLLLTLVVVTIVCLDFGHT
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Sequence Removed Signal Peptide
RICYNQQSSQPPTTKTCSEGQCYKKTWRDHRGTIIERGCACPNVKPGIQISCCTSDKCNG
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Disulfide Bond
24-43;38-60;62-73;74-79
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Elapidae
Genus: Micrurus
Species: Micrurus laticollaris
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-1-beta-1-gamma-delta IC50
1.4 nM
 . . [1]
 Target Info    nAChR alpha-1-beta-1-delta-epsilon IC50
12 nM
 . . [1]
 Target Info    nAChR alpha-7 IC50
400 nM
 . . [1]
References
Ref 1 Isolation, characterization, cloning and expression of an alpha-neurotoxin from the venom of the Mexican coral snake Micrurus laticollaris (Squamata: Elapidae). Toxicon. 2013 May;66:64-74. doi: 10.1016/j.toxicon.2013.02.006. Epub 2013 Feb 22.
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